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Marco Costanzi

Professore associato
Sede: Roma
Dipartimento: Scienze Umane (Comunicazione, Formazione, Psicologia)
Corso di laurea: Scienze e tecniche psicologiche

Insegnamenti e orario di ricevimento

  • Fondamenti genetici della psicologia

    Aula docenti 2° piano; piazza delle Vaschette, 101
    Mercoledì ore 14- 16
  • Psicobiologia fisiologica (con esperienze applicative)

    Aula docenti 2° piano; piazza delle Vaschette, 101
    Mercoledì ore 14-16
  • Curriculum Vitae

    Marco Costanzi si è laureato con lode in Psicologia nel 2001 all’Università “Sapienza” di Roma, dove ha ottenuto il dottorato in Neurofisiologia nel 2005. È iscritto all’albo degli psicologi della regione Lazio dal 2008. Attualmente è ricercatore a tempo indeterminato presso il Dipartimento di Scienze Umane dell’Università LUMSA ed è in possesso dell’Abilitazione Scientifica Nazionale a professore di seconda fascia per il settore concorsuale 11/E1 (s.s.d. M-PSI/02). Dal 2002 a oggi ha eseguito studi nell’Istituto di Neuroscienze e nell’Istituto di Biologia Cellulare e Neurobiologia del CNR sui meccanismi neurobiologici dei processi di apprendimento e memoria in condizioni fisiologiche e patologiche. 


    Principali pubblicazioni

    Costanzi M; D'Alessandro F; Saraulli D; Cannas S; Rossi-Arnaud C; Cestari V (2015). EVALUATING THREAT INTENSITY: A ROLE FOR THE LATERAL ORBITOFRONTAL CORTEX. EBBS - EBPS Verona Joint Meeting 2015.

    Mastrorilli V; Scopa C; Saraulli D; Costanzi M; Cestari V; Scardigli R; Tirone F; Farioli-Vecchioli S (2015). Impaired spatio-temporal coordination of cell cycle exit and migration in the adult subventricular zone is restored by physical exercise. Adult Neurogenesis: Evolution, Regulation and Function,.

    CESTARI V; SARAULLI D; FARIOLI-VECCHIOLI S; MASTRORILLI V; D'ALESSANDRO F; COSTANZI M; DEMARCHIS S; VENTURA R (2015). Neurogranin gene deletion increases stress responsivity in heterozygous mice. SFN 2015.

    Cestari V; Saraulli D; Pristerà A; Farioli-Vecchioli S; Strimpakos G; Di Certo MG; Costanzi M; Cannas S; Ciotti MT; Tirone F; Mattei E; Canu N (2014). Expression of pathological tau fragment in hippocampal neuronal precursor cells induces early symptoms of Alzheimer's disease in transgenic mice. 13th Annual Molecular and Cellular Cognition Society Meeting.

    Costanzi M; Saraulli D; Pristerà A; Farioli-Vecchioli S; Strimpakos G; Di Certo MG; Cannas S; Ciotti MT; Tirone F; Mattei E; Cestari V; Canu N (2014). Expression of pathological tau fragment in hippocampal neuronal precursor cells induces early symptoms of Alzheimer's disease in transgenic mice. . 9th Forum of European Neuroscience, Milan, July 5-9. .

    Costanzi M; Saraulli D; Cannas S; D'Alessandro F; Florenzano F; Rossi-Arnaud C; Cestari V (2014). Fear but not fright: re-evaluating traumatic experience attenuates anxiety-like behaviors after fear conditioning.. FRONTIERS IN BEHAVIORAL NEUROSCIENCE,

    Costanzi M; Saraulli D; Cannas S; D'Alessandro F; Florenzano F; Rossi-Arnaud C; Cestari V (2014). La ri-valutazione cognitiva dell'esperienza traumatica attenua l'attività dell'amigdala in un modello murino di PTSD.. XX Congresso Nazionale della Sezione di Psicologia Sperimentale AIP.

    Farioli-Vecchioli S; Mattera A; Micheli L; Ceccarelli M; Leonardi L; Saraulli D; Costanzi M; Cestari V; Rouault JP; Tirone F (2014). Running rescues defective adult neurogenesis by shortening the length of the cell cycle of neural stem and progenitor cells.. Adult Neurogenesis.

    Farioli-Vecchioli S; Mattera A; Micheli L; Ceccarelli M; Leonardi L; Saraulli D; Costanzi M; Cestari V; Rouault JP; Tirone F (2014). Running rescues defective adult neurogenesis by shortening the length of the cell cycle of neural stem and progenitor cells.. STEM CELLS,

    Cestari V; Rossi-Arnaud C; Saraulli D; Costanzi M (2014). The MAP(K) of fear: from memory consolidation to memory extinction.. BRAIN RESEARCH BULLETIN,

    Farioli-Vecchioli S; Ceccarelli M; Saraulli D; Micheli L; Cannas S; D'Alessandro F; Scardigli R; Leonardi L; Cinà I; Costanzi M; Mattera A; Cestari V; Tirone F. (2014). Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids.. FRONTIERS IN CELLULAR NEUROSCIENCE,

    Ceccarelli M; Farioli-Vecchioli S; Saraulli D; Micheli L; Cannas S; D'Alessandro F; Scardigli R; Leonardi L; Cinà I; Costanzi M; Cestari V; Tirone F (2014). Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids. . 9th Forum of European Neuroscience, Milan, July 5-9. .

    Canu N; Pristerà A; Saraulli D; Farioli-Vecchioli S; Strimpakos G; Costanzi M; Di Certo MG; Cannas S; Ciotti MT; Tirone F; Mattei E; Cestari V (2013). Expression of N-tau fragment in mouse hippocampal adult progenitor cells impairs neurogenesis and episodic-like memory.. 11th International Conference on Alzheimer's .

    Pristerà A; Saraulli D; Farioli-Vecchioli S; Strimpakos G; Costanzi M; di Certo MG; Cannas S; Ciotti MT; Tirone F; Mattei E; Cestari V; Canu N. (2013). Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory.. NEUROBIOLOGY OF AGING, vol. 34, 11, p.2551 - 2563

    Costanzi M; Saraulli D; D'Alessandro F; Cannas S; Rossi-Arnaud C; Cestari V (2013). Lateral or-bitofrontal cortex mediates fear memory re-evaluation in conditioned mice.. XV National Congress of the Italian Society of Neuroscience, Rome, October 3-5. .

    Costanzi M; D'Alessandro F; Saraulli D; Cannas S; Rossi-Arnaud C; Cestari V (2013). Ruolo della corteccia orbito-frontale nella rivalutazione di stimoli traumatici.. XIX Congresso di Psicologia sperimentale dell'Associazione Italiana di Psicologia, Rome, September 16-18..

    Strimpakos G; Pristerà A; Saraulli D; Farioli-Vecchioli S; Costanzi M; Di Certo MG; Cannas S; Ciotti MT; Tirone F; Cestari V; Mattei E; Canu N (2013). Transgenic expression of N-tau in neuronal precursor cells decreases adult hippocampal neurogenesis, increases anxiety-related behavior and impairs episodic like-memory. . 11th Transgenic Technology Meeting, Guangzhou, February 25-27. .

    Farioli-Vecchioli S; Micheli L; Saraulli D; Ceccarelli M; Cannas S; Scardigli R; Leonardi L; Cinà I; Costanzi M; Ciotti MT; Moreira P; Rouault JP; Cestari V; Tirone F (2012). Btg1 is Required to Maintain the Pool of Stem and Progenitor Cells of the Dentate Gyrus and Subventricular Zone. FRONTIERS IN NEUROGENESIS,

    Canu N; Pristerà A; Saraulli D; Farioli-Vecchioli S; Strimpakos G; Costanzi M; Di Certo MG; Cannas S; Ciotti MT; Tirone F; Mattei E; Cestari V (2012). Expression of N-tau fragment in hippo-campal adult progenitor cells impairs neurogenesis and episodic-like memory..

    Müller M; Triaca V; Besusso D; Costanzi M; Horn JM; Koudelka J; Geibel M; Cestari V; Minichiello L (2012). Loss of NGF-TrkA Signaling from the CNS Is Not Sufficient to Induce Cognitive Impairments in Young Adult or Intermediate-Aged Mice. THE JOURNAL OF NEUROSCIENCE, vol. 32, 43, p.14885 - 14898 , DOI: 10.1523/JNEUROSCI.2849-12.2012.

    Cestari V; Cannas S; Saraulli D; Rossi-Arnaud C; Costanzi M (2011). Effect of desensitization on remote contextual fear memory.. 8th IBRO World Congress of Neuroscience.

    CESTARI V; CANNAS S; SARAULLI D; ROSSI ARNAUD CM; COSTANZI M (2011). Extinction after retrieval of remote contextual fear memory fails to persistently attenuate the expression of fear memory. Program No. 202.28/XX79. 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2011. Online..

    Costanzi M; Cannas S; Saraulli D; Rossi-Arnaud C; Cestari V. (2011). Extinction after retrieval: effects on the associative and nonassociative components of remote contextual fear memory. LEARNING & MEMORY, vol. 18, 8, p.508 - 518 , DOI: 10.1101/lm.2175811

    Saraulli D; Farioli-Vecchioli S; Pristerà A; Strimpakos G; Costanzi M; Di Certo MG; Ciotti T; Tirone F; Mattei E; Cestari V; Canu N (2011). Mechanisms underlying the effect of N-terminal 26-230 tau fragment on synaptic dysfunction and neurodegeneration. 10th International Conference on Alzheimer's .

    Farioli Vecchioli S; Saraulli D; Costanzi M; Leonardi L; Cinà I; Micheli L; Nutini M; Longone P; Oh SP; Cestari V; Tirone F (2010). Essential role of pc3/tis21/btg2 gene in adult hippocampal neurogenesis. FENS Abstr.. vol. 5,

    Costanzi M; Saraulli D; Cannas S; Rossi-Arnaud CM; Cestari V (2010). Fear but not fright: effect of desensitization on fear conditioned memory. FENS Abstr.. vol. 5,

    Cannas S; Costanzi M; Saraulli D; Di Certo MG; Strimpakos G; Mattei E; Cestari V (2010). Genetic ablation of beta1- and beta2-adrenergic receptors protects from the onset of PTSD-like symptoms by reducing fear sensitization. FENS Abstr.. vol. 5,

    FARIOLI-VECCHIOLI S; SARAULLI D; COSTANZI M; LEONARDI L; CINA I; MICHELI L; NUTINI M; LONGONE P; OH P; CESTARI V; TIRONE F (2010). Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice. rogram No. 330.3/A3. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online..

    ROSSI-ARNAUD CM; CANNAS S; COSTANZI M; SARAULLI D; DI CERTO M; STRIMPAKOS G; MATTEI E; CESTARI V (2010). Protection from PTSD-like symptoms by reducing fear sensitization in mice lacking beta1- and beta2-adrenergic receptors. Program No. 705.17/LLL35. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online..

    BATASSA EM; COSTANZI M; SARAULLI D; SCARDIGLI R; BARBATO C; COGONI C; CESTARI V (2010). RISC activity in hippocampus is essential for contextual memory. NEUROSCIENCE LETTERS, vol. 471, 3, p.185 - 188

    Saraulli D; Costanzi M; Cannas S; Rossi-Arnaud CM; Cestari V (2010). What is PTSD made of? Differential contribution of traumatic memory and sensitization to the onset of symptoms. FENS Abstr.. vol. 5,

    FARIOLI-VECCHIOLI S; SARAULLI D; COSTANZI M; LEONARDI L; CINà I; MICHELI L; NUTINI M; LONGONE P; OH SP; CESTARI V; TIRONE F (2009). Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice. PLOS ONE, vol. 4, 12, p.e8339

    COSTANZI M; SARAULLI D; ROSSI-ARNAUD C; ACETI M.. AND CESTARI V (2009). Memory impairment induced by an interfering task is reverted by pre-frontal cortex lesions: a possible role for an inhibitory process in memory suppression in mice. NEUROSCIENCE, vol. 158, 2, p.503 - 513

    SARAULLI D; FARIOLI-VECCHIOLI S; COSTANZI M; PACIONI S; CINà I ACETI M; MICHELI L; BACCI A; CESTARI V; TIRONE F (2009). The timing of differentiation of adult hippocampal neurons is crucial for spatial memory. Program No. 581.10/GG62. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online..

    MUSUMECI G; SCIARRETTA C; RODRíGUEZ-MORENO A; AL BANCHAABOUCHI M; NEGRETE-DíAZ V; COSTANZI M; BERNO V; EGOROV AV; VON BOHLEN UND HALBACH O; CESTARI V; DELGADO-GARCíA JM; MINICHIELLO L (2009). TrkB modulates fear learning and amygdalar synaptic plasticity by specific docking sites. THE JOURNAL OF NEUROSCIENCE, vol. 29, 32, p.10131 - 10143

    Cestari V; Batassa EM; Costanzi M; Saraulli D; Barbato C; Cogoni C (2008). A role for Argonaute2 protein in memory formation in mice. Program No. 688.14. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. .

    Rossi-Arnaud CM; Cestari V; Saraulli D; Aceti M; Costanzi M (2008). Prefrontal cortex lesions rescue short-term memory impairment induced by an interfering task: a possible role for an inhibitory process in memory suppression in CD1 mice. . Program No. 688.15/TT34. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2008. Online. .

    Cestari V; Saraulli D; Rossi-Arnaud CM; Canu N; Barbato V; Aceti M; Costanzi M (2008). Ras-GRF1 memory deficit in the inhibitory avoidance task is rescued by a two-learning-trials procedure.. FENS Abstr.. vol. 4,

    FARIOLI-VECCHIOLI S; SARAULLI D; COSTANZI M; PACIONI S; CINà I; ACETI M; MICHELI L; BACCI A; CESTARI V; TIRONE F (2008). The Timing of Differentiation of Adult Hippocampal Neurons is Crucial for Spatial Memory. PLOS BIOLOGY, vol. 6, 10, p.e246

    Costanzi M; Cestari V and Castellano C (2007). A POSSIBLE ROLE FOR INTRACELLULAR PATHWAYS ACTIVATION IN THE MODULATION OF LEARNING AND MEMORY PROCESSES BY THE DOPAMINERGIC AND OPIOID SYSTEMS INTERACTION. (a cura di) Akiyama Watanabe, Dopamine Research Advances. , ISBN: 978-1-60021-820-0

    SARAULLI D; CESTARI V; ROSSI-ARNAUD CM; BARBATO V; ACETI M; COSTANZI M (2007). Memory rescue in Ras-GRF1 knockout mice submitted to a two-trial learning procedure in an inhibitory avoidance task. Program No. 639.15/FFF31. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online..

    CESTARI V; COSTANZI M; ROSSI-ARNAUD C. AND CASTELLANO C (2006). A role for ERK2 in reconsolidation of fear memories in mice. NEUROBIOLOGY OF LEARNING AND MEMORY, vol. 86, 2, p.133 - 143

    Amadoro G; Ciotti MT; Costanzi M; Cestari V; Calissano P; Canu N (2006). Molecular mechanisms underlying tau induced neurotoxicity.. FENS Forum Abstracts. vol. 3,

    AMADORO G; CIOTTI M.T; COSTANZI M; CESTARI V; CALISSANO P; CANU N (2006). NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 103, 8, p.2892 - 2897

    CESTARI V; ROSSI-ARNAUD C; ACETI M; COSTANZI M (2006). Retention of a spatial task associated with emotionally arousing information in mice and humans: the effect of a spatial interference task. Program No. 575.6/MM31. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, 2006. Online..

    Cestari V; Aceti M; Rossi Arnaud C; Mazza A; Costanzi M (2006). The effect on retention of spatial interference in mice submitted to a step-through inhibitory avoidance task.. FENS Forum Abstracts. vol. 3,

    Cestari V; Pasparakis M; De Lorenzi R; Costanzi M; Rossi-Arnaud CM (2005). Molecular mechanisms of hippocampal-dependent learning and memory: a behavioral analysis of neuron-restricted IKK2 knock-out mice.. Program No. 996.14. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online..

    Canu N; Amadoro G; Ciotti M; Costanzi M; Cestari V; Calissano P (2005). Tau N-terminal-linked degeneration in primary neuronal cultures is mediated by activation of NMDA receptor and MAP kinase pathway.. Program No. 207.12. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online..

    Cestari V; Sciarretta C; Costanzi M; Rossi Arnaud C; Minichiello L (2004). Distinct involvement of the PLCgamma-site and the Shc-site of the TrkB neurotrophin receptor in behaviour.. FENS Forum Abstracts. vol. 2,

    COSTANZI M; BATTAGLIA M; ROSSI-ARNAUD C; CESTARI V. AND CASTELLANO C (2004). Effects of anandamide and morphine combinations on memory consolidation in CD1 mice: involvement of dopaminergic mechanisms.. NEUROBIOLOGY OF LEARNING AND MEMORY, vol. 81, 2, p.144 - 149

    Rossi-Arnaud CM; Costanzi M; Castellano C; Cestari V (2004). Role of MAP kinases in reconsolidation after retrieval of fear memories.. Program No. 327.14 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online..

    COSTANZI M; BATTAGLIA M; POPULIN R; CESTARI V. AND CASTELLANO C (2003). Anandamide and memory in CD1 mice: effects of immobilization stress and of prior experience. NEUROBIOLOGY OF LEARNING AND MEMORY, vol. 79, 3, p.204 - 211

    Rossi-Arnaud CM; Costanzi M; Battaglia M; Cestari V; Castellano C (2003). Anandamide potentiates morphine-induced impairment of memory consolidation in CD1 mice: involvement of dopaminergic mechanisms.. Program No. 539.12 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online..

    CASTELLANO C; ROSSI-ARNAUD C; CESTARI V; COSTANZI M (2003). Cannabinoids and memory: animal studies. CURRENT DRUG TARGETS. CNS & NEUROLOGICAL DISORDERS, vol. 2, 6, p.389 - 402

    Cestari V; Costanzi M; Rossi-Arnaud CM; Castellano C (2002). EFFECTS OF ANANDAMIDE ON MEMORY CONSOLIDATION: ROLE OF ENVIRONMENTAL FACTORS.. Program No. 783.15. 2002 Neuroscience Meeting Planner. Orlando, FL: Society for Neuroscience, 2002. Online..

    Marucci FS; Costanzi M (2002). Il trasferimento di conoscenza nella soluzione di problemi analogici: l'effetto di differenti suggerimenti impliciti. . In: M. Bagassi, L. Macchi e M.G. Serafini . Discorsi e pensieri, scritti in onore di Giuseppe Mosconi. . BOLOGNA:Il Mulino, p.237 - 243 , ISBN: 9788815083920

    Consiglio A; Quattrini A; Martino S; Bensadoun JC; Dolcetta D; Trojani A; Cestari V; Oliverio A; Costanzi M; Bordignon C; Naldini L (2000). In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: protection from neuropathology and learning impairments in mice.. Program No. 668.2. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online..

    Saraulli D; Costanzi M; Mastrorilli V; Farioli-Vecchioli S (In stampa) The long run: neuroprotective effects of physical exercise on adult neurogenesis from youth to old age. CURRENT NEUROPHARMACOLOGY,


    Corsi di Laurea Master e Post Laurea